TargetMol

DDO3711

Product Code:
 
TAR-T73460
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T73460-5mg5mg£930.00
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TAR-T73460-50mg50mg£1,821.00
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Quantity:
TAR-T73460-100mg100mg£2,319.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DDO3711, a PP5-recruiting phosphatase recruitment chimeras (PHORCs), is formed by connecting a small molecular apoptosis signal-regulated kinase 1 (ASK1) inhibitor to a PP5 activator through a chemical linker. DDO3711 specifically inhibits ASK1 ( IC 50 =164.1 nM) not ASK2 (IC 50 >20 uM). DDO3711 significantly dephosphorylates p-ASK1 T838 by recruiting PP5 and shows the ASK1-dependent antiproliferative activity. DDO3711 has anti-cancer activity and has the potential for abnormally phosphorylated oncoproteins research .
CAS:
2673364-10-6
Molecular Weight:
767.83
Purity:
0.98
SMILES:
O=C(NC=1N=C2C=CC(=CN2C1)N3C=NC=C3)C4=CC=C(C=C4)C(=O)NCCCCCCNC(=O)C5=CC=C(C=C5)CC6=NOC(=N6)C=7C=CC(OC)=C(OC)C7