TargetMol

YKL-5-124 TFA

Product Code:
 
TAR-T73633
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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TAR-T73633-50mg50mgEnquire
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TAR-T73633-5mg5mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
YKL-5-124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC 50 s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH , respectively. YKL-5-124 TFA is >100-fold greater selective for CDK7 than CDK9 and CDK2 , and inactive against CDK12 and CDK13 . YKL-5-124 TFA induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status [1] .
CAS:
2748220-93-9
Formula:
C30H34F3N7O5
Molecular Weight:
629.63
Purity:
0.98