TargetMol

cis-Lomibuvir

Product Code:
 
TAR-T73814
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T73814-50mg50mgEnquire
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TAR-T73814-5mg5mgEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
cis-Lomibuvir (cis-VX-222) is the cis-isomer of Lomibuvir. Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a K d of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an?EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than?de novo-initiated RNA synthesis [1] .
CAS:
1026785-59-0
Molecular Weight:
445.61
Purity:
0.98
SMILES:
C[C@H]1CC[C@@H](CC1)C(=O)N([C@@H]1CC[C@@H](CC1)O)c1c(sc(c1)C#CC(C)(C)C)C(=O)O