TargetMol

P053

Product Code:
 
TAR-T12342
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T12342-25mg25mg£1,267.00
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Quantity:
TAR-T12342-50mg50mg£2,070.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor with an IC50 of 0.5 uM. P053 is an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle and regulator of whole-body adiposity[1].
CAS:
2748196-63-4
Formula:
C18H21Cl2NO2
Molecular Weight:
354.27
Purity:
0.98
SMILES:
OC[C@@](C)(N)CCC1=CC=C(OCC2=CC=C(Cl)C(Cl)=C2)C=C1

References

Turner N, et al. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nat Commun. 2018 Aug 21;9(1):3165.