TargetMol

Calpain Inhibitor XII

Product Code:
 
TAR-T21949
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T21949-25mg25mg£1,010.00
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This product comes from: United States.
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Further Information

Bioactivity:
(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (u-calpain) with Ki of 19 nM. (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, K i =120 nM) and cathepsin B (K i =750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury [1].
CAS:
181769-57-3
Molecular Weight:
482.57
Purity:
0.98
SMILES:
O=C(OCC=1C=CC=CC1)NC(C(=O)NC(C(=O)C(=O)NCC2=NC=CC=C2)CCC)CC(C)C