TargetMol

Pomalidomide-amino-PEG4-NH2

Product Code:
 
TAR-T39866
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Pomalidomide-amino-PEG4-NH2 is a conjugate compound that combines the Pomalidomide-based cereblon ligand and a linker, effectively functioning as a synthesized E3 ligase ligand-linker conjugate utilized in PROTAC technology.
CAS:
2331259-44-8
Molecular Weight:
506.512
Purity:
0.98
SMILES:
NCCOCCOCCOCCOCC(=O)Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

References

Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.