TargetMol

4-PQBH

Product Code:
 
TAR-T61428
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
4-PQBH is a potent binder of Nur77, with a binding affinity of 1.17 uM. It promotes caspase-independent cytoplasmic vacuolization and paraptosis through Nur77-mediated endoplasmic reticulum (ER) stress and autophagy. The compound, 4-PQBH, holds potential for cancer research applications [1].
CAS:
2243355-51-1
Formula:
C22H17N5O
Molecular Weight:
367.412
Purity:
0.98
SMILES:
O=C(NN=Cc1ccncc1)c1ccc(Nc2ccnc3ccccc23)cc1