TargetMol

TPX-0131

Product Code:
 
TAR-T9414
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T9414-50mg50mg£1,315.00
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Quantity:
TAR-T9414-100mg100mg£1,869.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TPX-0131 is a potent, selective, CNS-penetrant and orally active inhibitor of wild-type ALK ( IC 50 of 1.4 nM) and is potent against ALK-resistant mutation, e.g. G1202R ( IC 50 of 0.3 nM), L1196M ( IC 50 of 0.3 nM). TPX-0131 has strong antitumor activities [1].
CAS:
2648641-36-3
Molecular Weight:
447.418
Purity:
0.98
SMILES:
CC1(C)COc2ccc(F)cc2CN2[C@@H](COc3cn4ncc(C(=O)N1)c4nc23)C(F)F