TargetMol

Doxepin D3 Hydrochloride

Product Code:
 
TAR-T11088
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Doxepin D3 Hydrochloride is a deuterium-labeled doxepin hydrochloride.Doxepin hydrochloride is an oral active tricyclic antidepressant used as a sedative.Doxepin hydrochloride is also an effective CYP450 inhibitor, significantly inhibiting CYP450 2C19 and 1A2.Doxepin hydrochloride is an effective selective histamine receptor H1 antagonist.
CAS:
347840-07-7
Formula:
C19H22ClNO
Molecular Weight:
318.86
Pathway:
Immunology/Inflammation|GPCR/G Protein|Neuroscience
Purity:
0.98
SMILES:
Cl.[2H]C([2H])([2H])N(C)CCC=C1c2ccccc2COc2ccccc12 |w:9.7|
Target:
Histamine Receptor

References

Gillman PK1. Tricyclic antidepressant pharmacology and therapeutic drug interactions updated. Br J Pharmacol. 2007 Jul;151(6):737-48. Hajak, G., et al., Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic study. J Clin Psychiatry, 2001. 62(6): p. 453-63.