TargetMol

Rivaroxaban-d4

Product Code:
 
TAR-T12736
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
CAS:
1132681-38-9
Formula:
C19H18ClN3O5S
Molecular Weight:
439.91
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C1N(C[C@H](CNC(=O)C=2SC(Cl)=CC2)O1)C3=C(C(=C(C(=C3[2H])[2H])N4C(=O)COCC4)[2H])[2H]
Target:
Factor Xa

References

Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3(3):514-21. Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19)