TargetMol

Maleimido-tri(ethylene glycol)-propionic acid

Product Code:
 
TAR-T16008
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1].
CAS:
518044-40-1
Formula:
C13H19NO7
Molecular Weight:
301.29
Purity:
0.98
SMILES:
O=C(O)CCOCCOCCOCCN1C(=O)C=CC1=O

References

Zhou D,et al. Novel PIKK inhibitor antibody-drug conjugates: Synthesis and anti-tumor activity.Bioorg Med Chem Lett. 2019 Apr 1;29(7):943-947.