TargetMol

Mal-C6-α-Amanitin

Product Code:
 
TAR-T18249
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T18249-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T18249-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.
CAS:
1578249-76-9
Molecular Weight:
1211.34
Purity:
0.98
SMILES:
O=[S@@]1C2=C(C=3C(N2)=CC(OCCCCCCNC(CCCCCN4C(=O)C=CC4=O)=O)=CC3)C[C@@]5(NC(=O)[C@]([C@H]([C@H](CO)O)C)(NC(=O)[C@]6(N(C(=O)[C@](CC(N)=O)(NC(=O)[C@](C1)(NC(=O)CNC(=O)[C@]([C@H](CC)C)(NC(=O)CNC5=O)[H])[H])[H])C[C@H](O)C6)[H])[H])[H]

References

Brian Lannutti,et al. Ror1 antibody immunoconjugates. WO2018237335A1.