TargetMol

MC-VC-PABC-Aur0101

Product Code:
 
TAR-T18332
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
MC-VC-PABC-Aur0101 is a drug-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC.
CAS:
1438849-92-3
Molecular Weight:
1341.66
Purity:
0.98
SMILES:
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C2=NC=CS2)=O)C)(OC)[C@]3(N(C(C[C@H]([C@@H](N(C([C@@H](NC(C(NC(OCC4=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN5C(=O)C=CC5=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C4)=O)(C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC3)[H]

References

Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.