TargetMol

mDPR(Boc)-Val-Cit-PAB

Product Code:
 
TAR-T18333
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
mDPR(Boc)-Val-Cit-PAB is a cleavable linker employed in antibody-drug conjugates (ADCs) [1]. This chemical compound serves as a reliable linker in the formation of ADCs, which are biopharmaceuticals that combine the specificity of monoclonal antibodies with the potency of cytotoxic drugs for targeted cancer therapy [1].
CAS:
2281797-55-3
Molecular Weight:
645.7
Purity:
0.98
SMILES:
[C@@H](C(N[C@H](C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)CCCNC(N)=O)=O)[C@@H](C)C)=O)(CNC(OC(C)(C)C)=O)N2C(=O)C=CC2=O

References

LYON, Robert, et al. SELF-STABILIZING LINKER CONJUGATES. WO2013173337.