TargetMol

Methyltetrazine-PEG4-SS-NHS ester

Product Code:
 
TAR-T18351
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Methyltetrazine-PEG4-SS-NHS ester is a cleavable, four-unit polyethylene glycol (PEG) linker commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
T18351
Molecular Weight:
737.84
Purity:
0.98
SMILES:
CC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)=O)C=C2)N=N1

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.