TargetMol

Methyltetrazine-PEG4-SS-PEG4-methyltetrazine

Product Code:
 
TAR-T18352
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit polyethylene glycol (PEG) linker, employed for the synthesis of antibody-drug conjugates (ADCs)[1].
CAS:
T18352
Molecular Weight:
1071.27
Purity:
0.98
SMILES:
O=C(CCOCCOCCOCCOCCNC(CCSSCCC(NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O)=O)NCC3=CC=C(C4=NN=C(C)N=N4)C=C3

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.