TargetMol

Grayanotoxin III

Product Code:
 
TAR-T31994
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T31994-100mg100mgEnquire
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TAR-T31994-500mg500mgEnquire
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Further Information

Bioactivity:
Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana, a plant native to Japan originally. Extract from leaves Leucothoe grayana (Ericaceae).
CAS:
4678-45-9
Molecular Weight:
370.486
Purity:
0.98
SMILES:
[H][C@]12CC[C@]3([H])[C@@](C[C@@]1(C)O)(C[C@@H](O)[C@@]1(O)[C@@]([H])(C[C@H](O)C1(C)C)[C@]3(C)O)C2O |TLB:28:27:4.3.2:8.7|

References

Lim MY, Phua DH, Ooi CK. Heart stopping honey-not just Turkish honey. Am J Emerg Med. 2016 Sep;34(9):1915.e1-3. doi: 10.1016/j.ajem.2016.02.014. Epub 2016 Feb 13. PubMed PMID: 26947374. Hwang T, Noh E, Jeong JH, Park SK, Shin D, Kang H. Determination of Grayanotoxins from Rhododendron brachycarpum in Dietary Supplements and Homemade Wine by Liquid Chromatography-Quadrupole Time-of-Flight-Mass Spectrometry and Liquid Chromatography-Tandem Mass Spectrometry. J Agric Food Chem. 2018 Feb 28;66(8):1935-1940. doi: 10.1021/acs.jafc.7b05054. Epub 2018 Feb 20. PubMed PMID: 29433311. Choi HL, Park KH, Park JS, Choi HY, Kim H, Kim SM. Relationship between blood toxin level and clinical features in patients with grayanotoxin poisoning - six clinical cases. Clin Toxicol (Phila). 2017 Nov;55(9):991-995. doi: 10.1080/15563650.2017.1331448. Epub 2017 Jun 8. PubMed PMID: 28594250. Aygun A, Gunduz A, Turedi S, Turkmen S, Karaca Y, Ayaz FA, Ahn SY, Kim S. Examination using LC-MS/MS determination of grayanotoxin levels in blood, urine, and honey consumed by patients presenting to the emergency department with mad honey intoxication and relations with clinical data: a preliminary study. Ann Saudi Med. 2015 Mar-Apr;35(2):161-4. doi: 10.5144/0256-4947.2015.161. PubMed PMID: 26336024; PubMed Central PMCID: PMC6074137.