TargetMol

Lysine alpha-ketoisovalerate

Product Code:
 
TAR-T33047
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Lysine alpha-ketoisovalerate is a bioactive chemical.
CAS:
78000-30-3
Molecular Weight:
262.3
Purity:
0.98
SMILES:
[C@H](CCCCN)(C(O)=O)N.C(C(C)C)(C(O)=O)=O

References

Hu H, Jaskiewicz JA, Harris RA. Ethanol and oleate inhibition of alpha-ketoisovalerate and 3-hydroxyisobutyrate metabolism by isolated hepatocytes. Arch Biochem Biophys. 1992 Nov 15;299(1):57-62. PubMed PMID: 1444452. Buchholz J, Schwentner A, Brunnenkan B, Gabris C, Grimm S, Gerstmeir R, Takors R, Eikmanns BJ, Blombach B. Platform engineering of Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate. Appl Environ Microbiol. 2013 Sep;79(18):5566-75. doi: 10.1128/AEM.01741-13. Epub 2013 Jul 8. PubMed PMID: 23835179; PubMed Central PMCID: PMC3754147. Aevarsson A, Seger K, Turley S, Sokatch JR, Hol WG. Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes. Nat Struct Biol. 1999 Aug;6(8):785-92. PubMed PMID: 10426958. Ro HS, Hong SP, Seo HJ, Yoshimura T, Esaki N, Soda K, Kim HS, Sung MH. Site-directed mutagenesis of the amino acid residues in beta-strand III [Val30-Val36] of D-amino acid aminotransferase of Bacillus sp. YM-1. FEBS Lett. 1996 Dec 2;398(2-3):141-5. PubMed PMID: 8977094.