PBP1

Product Code:

TAR-T33893

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20°C

No additional charges, what you see is what you pay! *

Code	Size	Price

TAR-T33893-100mg

100mg

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TAR-T33893-500mg

500mg

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Further Information

Bioactivity:

PBP1 is a selective inducer of i-motif structures from the unstructured single-stranded DNA conformations which upregulates BCL-2 gene expression in cancer cells.

CAS:

T33893

Molecular Weight:

804.92

Purity:

0.98

SMILES:

O=C(C1=NC(C(NCC2=CN(C3=CC=C(NC([C@H]4NCCC4)=O)C=C3)N=N2)=O)=CC(OCCCN(C)C)=C1)NCC5=CN(C6=CC=C(NC([C@H]7NCCC7)=O)C=C6)N=N5

Documents

References

Ostrowski LA, Hall AC, Szafranski KJ, Oshidari R, Abraham KJ, Chan JNY, Krustev C, Zhang K, Wang A, Liu Y, Guo R, Mekhail K. Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats. Commun Biol. 2018 Nov 5;1:187. doi: 10.1038/s42003-018-0187-3. eCollection 2018. PubMed PMID: 30417124; PubMed Central PMCID: PMC6218562. Plata KB, Riosa S, Singh CR, Rosato RR, Rosato AE. Targeting of PBP1 by ?-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains. PLoS One. 2013 Apr 23;8(4):e61083. doi: 10.1371/journal.pone.0061083. Print 2013. PubMed PMID: 23637786; PubMed Central PMCID: PMC3634065.