TargetMol

RH 421

Product Code:
 
TAR-T34313
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T34313-500mg500mgEnquire
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Further Information

Bioactivity:
RH 421 is an amphiphilic styryl dye.
CAS:
107610-19-5
Molecular Weight:
498.72
Purity:
0.98
SMILES:
O=S(=O)([O-])CCCC[N+]1=CC=C(C=CC=CC2=CC=C(C=C2)N(CCCCC)CCCCC)C=C1

References

Mikha?lova EV, Efimova SS, Ostroumova OS. [The effects of RH 421 on the activity of amphotericin B in cell and model membranes]. Tsitologiia. 2013;55(2):136-9. Russian. PubMed PMID: 23718076. Chulkov EG, Schagina LV, Ostroumova OS. Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore. Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):192-9. doi: 10.1016/j.bbamem.2014.09.004. Epub 2014 Sep 16. PubMed PMID: 25223717. Apetrei A, Mereuta L, Luchian T. The RH 421 styryl dye induced, pore model-dependent modulation of antimicrobial peptides activity in reconstituted planar membranes. Biochim Biophys Acta. 2009 Aug;1790(8):809-16. doi: 10.1016/j.bbagen.2009.04.002. Epub 2009 Apr 9. PubMed PMID: 19362116. Ostroumova OS, Efimova SS, Mikhailova EV, Schagina LV. The interaction of dipole modifiers with amphotericin-ergosterol complexes. Effects of phospholipid and sphingolipid membrane composition. Eur Biophys J. 2014 May;43(4-5):207-15. doi: 10.1007/s00249-014-0946-0. Epub 2014 Feb 23. PubMed PMID: 24563224.