TargetMol

VUF-11222

Product Code:
 
TAR-T35085
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
VUF-11222 is an agonist of high affinity non-peptide CXCR3 agonist (pKi = 7.2).
CAS:
1414376-84-3
Molecular Weight:
552.33
Purity:
0.98
SMILES:
C([N+](CC1=CC=C(C=C1)C2=C(Br)C=CC=C2)(C)C)C=3[C@]4(C(C)(C)[C@](C4)(CC3)[H])[H].[I-]

References

Wijtmans M, Scholten DJ, Roumen L, Canals M, Custers H, Glas M, Vreeker MC, de Kanter FJ, de Graaf C, Smit MJ, de Esch IJ, Leurs R. Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands. J Med Chem. 2012 Dec 13;55(23):10572-83. doi: 10.1021/jm301240t. Epub 2012 Nov 14. PubMed PMID: 23150943.