TargetMol

Renin inhibitory peptide

Product Code:
 
TAR-TP2351
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Renin inhibitory peptide is an analog of angiotensinogen.
CAS:
75645-19-1
Molecular Weight:
1318.52
Purity:
0.98
SMILES:
C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCCN2)(=O)N3[C@H](C(N[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@@H](CC6=CC=C(O)C=C6)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](C)C)=O)=O)CC7=CC=CC=C7)=O)=O)CC8=CC=CC=C8)=O)CCC3

References

Fitzgerald C, Aluko RE, Hossain M, Rai DK, Hayes M. Potential of a renin inhibitory peptide from the red seaweed Palmaria palmata as a functional food ingredient following confirmation and characterization of a hypotensive effect in spontaneously hypertensive rats. J Agric Food Chem. 2014 Aug 20;62(33):8352-6. doi: 10.1021/jf500983n. Epub 2014 Aug 7. PubMed PMID: 25062358. Thaisrivongs S, Pals DT, DuCharme DW, Turner SR, DeGraaf GL, Lawson JA, Couch SJ, Williams MV. Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys. J Med Chem. 1991 Feb;34(2):633-42. PubMed PMID: 1995887. Lafarga T, Rai DK, O'Connor P, Hayes M. A Bovine Fibrinogen-Enriched Fraction as a Source of Peptides with in Vitro Renin and Angiotensin-I-Converting Enzyme Inhibitory Activities. J Agric Food Chem. 2015 Oct 7;63(39):8676-84. doi: 10.1021/acs.jafc.5b03167. Epub 2015 Sep 28. PubMed PMID: 26373334. Fitzgerald C, Mora-Soler L, Gallagher E, O'Connor P, Prieto J, Soler-Vila A, Hayes M. Isolation and characterization of bioactive pro-peptides with in vitro renin inhibitory activities from the macroalga Palmaria palmata. J Agric Food Chem. 2012 Aug 1;60(30):7421-7. doi: 10.1021/jf301361c. Epub 2012 Jul 19. PubMed PMID: 22747312.