anti-IL-23p19 (human), mAb (I 178G)

Interleukin-23 Subunit p19; Interleukin-23 Subunit alpha; IL-23-A

1mg/ml

32160000

liquid

Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.

After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.

Recombinant human IL-23p19.

Monoclonal Antibody. Recognizes human IL-23p19. Isotype: Rat IgG2akappa. Clone: I 178G. Applications: ELISA, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Q9NPF7

Plastic Vial

IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Recognizes human IL-23p19.

Non-hazardous

Primary Antibodies

12352203

Stable for at least 1 year after receipt when stored at -20°C.