AdipoGen Life Sciences

NSC697923

Product Code:
 
AG-CR1-3519
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
Storage:
 
+4°C
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Chemical Structure
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Chemical Structure

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Further Information

Alternate Names/Synonyms:
2-(4-Methylphenyl)sulfonyl-5-nitrofuran
Appearance:
White solid.
CAS:
343351-67-7
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light.
InChi:
InChI=1/C11H9NO5S/c1-8-2-4-9(5-3-8)18(15,16)11-7-6-10(17-11)12(13)14/h2-7H,1H3
InChiKey:
GAUHIPWCDXOLCZ-UHFFFAOYAJ
Long Description:
Chemical. CAS: 343351-67-7. Formula: C11H9NO5S. MW: 267.3. Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kappaB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (diffuse large B cell lymphoma) cells.
MDL:
MFCD01925132
Molecular Formula:
C11H9NO5S
Molecular Weight:
267.3
Package Type:
Vial
Product Description:
Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kappaB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (diffuse large B cell lymphoma) cells.
Purity:
>98% (NMR)
SMILES:
CC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(O1)[N+]([O-])=O
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A: M. Pulvino, et al.; Blood 120, 1668 (2012)