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6-(Fluorescein-5(6)-carboxamido)hexanoicacid N-succinimidyl ester

Product Code:
 
CDX-F0044
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
-20°C
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Chemical Structure
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Chemical Structure

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CDX-F0044-M0055 mg£121.00
Quantity:
CDX-F0044-M02525 mg£450.00
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Further Information

Alternate Names/Synonyms:
6-(Fluorescein-5(6)-carboxamido)hexanoicacid N-succinimidyl ester; 5(6)-FAM-X, SE; C6-F-NHS; FHS
Appearance:
Yellow to orange powder.
CAS:
114616-31-8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C20H12O5.C12H18N2O5/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;1-9(15)13-8-4-2-3-5-12(18)19-14-10(16)6-7-11(14)17/h1-10,21-22H;2-8H2,1H3,(H,13,15)
InChiKey:
AZTAZTWVNFVDPK-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 114616-31-8. Formula: C31H26N2O10. MW: 586.6. Synthetic. Amine-reactive fluorescent probe for introducing a fluorescein label at a nucleophilic residue of a target molecule. This fluorescein labeling reagent has an added (X) spacer to improve accessibility of the reactive group by nucleophiles in preparation of bioconjugates. The reactive N-hydroxysuccinimide (NHS) group can be used for easy attachment to proteins or amine containing nucleotides using simple procedures. Spectral properties: lambdaex 490 nm; lambdaem 514 nm in DMF (pH 8.2) and lambdaex 491 nm; lambdaem 515 nm in 0.1 M Tris pH 9.0.
MDL:
MFCD00467542
Molecular Formula:
C31H26N2O10
Molecular Weight:
586.6
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
Amine-reactive fluorescent probe for introducing a fluorescein label at a nucleophilic residue of a target molecule. This fluorescein labeling reagent has an added (X) spacer to improve accessibility of the reactive group by nucleophiles in preparation of bioconjugates. The reactive N-hydroxysuccinimide (NHS) group can be used for easy attachment to proteins or amine containing nucleotides using simple procedures. Spectral properties: lambdaex 490 nm; lambdaem 514 nm in DMF (pH 8.2) and lambdaex 491 nm; lambdaem 515 nm in 0.1 M Tris pH 9.0.
Purity:
>75% (HPLC)
Signal word:
Warning
SMILES:
O=C(C1=C2C=CC=C1)OC32C4=C(C=C(O)C=C4)OC5=CC(O)=CC=C53.CC(NCCCCCC(ON6C(CCC6=O)=O)=O)=O
Solubility Chemicals:
Soluble in dimethylformamide or methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) G.P. Jamieson, et al.; Cytometry 14, 32 (1993) | (2) K.A. Cruickshank; Anal. Biochem. 269, 21 (1999) | (3) J.J. MacLean, et al.; Biophys. J. 78, 1441 (2000) | (4) W.C. Cooper, et al.; Biophys. J. 78, 1449 (2000) | (5) M.P. Gygi, et al.; Nucleic Acids Res. 30, 2790 (2002)