AdipoGen Life Sciences

ZSTK474

Product Code:
 
SYN-1099
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
1 / 1
Chemical Structure
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Chemical Structure

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Further Information

Alternate Names/Synonyms:
ZSTK-474
Appearance:
Solid.
CAS:
475110-96-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
InChiKey:
HGVNLRPZOWWDKD-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 475110-96-4. Formula: C19H21F2N7O2. MW: 417.4. ZSTK474 Inhibits all four PI3K isoforms in an ATP-competitive manner. IC(50) is approximately 37nM.
Molecular Formula:
C19H21F2N7O2
Molecular Weight:
417.4
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
ZSTK474 Inhibits all four PI3K isoforms in an ATP-competitive manner. IC(50) is approximately 37nM.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor: S. Yaguchi, et al.; J. Natl. Cancer Inst. 98, 545 (2006)