Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Phosphatidylinositol 3,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,5)-dependent Rac exchanger 1, PREX1, KIAA1415
For WB starting dilution is: 1:1000
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
- Carretero-Ortega, J., et al. Mol. Pharmacol. 77(3):435-442(2010)
- Ledezma-Sanchez, B.A., et al. Biochem. Biophys. Res. Commun. 391(4):1647-1652(2010)
- Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
- Qin, J., et al. Oncogene 28(16):1853-1863(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-594 amino acids from the Central region of human PREX1.
57580
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
PREX1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
186 kDa
Q8TCU6
148886999
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Signal Transduction
Q8TCU6
Optimal dilutions for each application to be determined by the researcher.