Further Information
ATP-dependent RNA helicase DDX3Y, DEAD box protein 3, Y-chromosomal, DDX3Y, DBY
For WB starting dilution is: 1:1000
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
and it has a homolog on the X chromosome. The gene mutation causes
male infertility, Sertoli cell-only syndrome or severe
hypospermatogenesis, suggesting that this gene plays a key role in
the spermatogenic process. Alternatively spliced variants, encoding
the same protein, have been identified.
- Rosinski, K.V., et al. Blood 111(9):4817-4826(2008)
- Lardone, M.C., et al. Mol. Hum. Reprod. 13(10):705-712(2007)
- Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005) :
- Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This DDX3Y antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human DDX3Y.
8653
ATP-dependent RNA helicase DDX3Y
DDX3Y
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
O15523
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Signal Transduction
O15523
Optimal dilutions for each application to be determined by the researcher.