ProSci

CAPG Antibody

Product Code:
 
PSI-58-235
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-58-235-400ul400ul£626.00
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Further Information

Additional Names:
Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq].
Background References:
  • Li, M.X., et al. Med. Oncol. 27(1):134-144(2010)
  • Burillo, E., et al. Atherosclerosis 207(1):32-37(2009)
  • Zhang, R., et al. Am. J. Respir. Cell Mol. Biol. 41(4):467-475(2009)
  • Hubert, T., et al. Biochem. Biophys. Res. Commun. 380(1):166-170(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human CAPG.
NCBI Gene ID #:
822
NCBI Official Name:
Macrophage-capping protein
NCBI Official Symbol:
CAPG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
P40121
Protein GI Number:
313104088
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P40121
User NOte:
Optimal dilutions for each application to be determined by the researcher.