ProSci

PANK1 Antibody

Product Code:
 
PSI-62-693
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis of anti-PANK1 Pab in mouse kidney tissue lysate (35ug/lane).
2 / 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
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Western blot analysis of anti-PANK1 Pab in mouse kidney tissue lysate (35ug/lane).
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

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PSI-62-693-400ul400ul£626.00
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Further Information

Additional Names:
Pantothenate kinase 1, hPanK, hPanK1, Pantothenic acid kinase 1, PANK1, PANK
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
PANK1 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA.
Background References:
  • Ramaswamy, G., et al., J. Lipid Res. 45(1):17-31 (2004).
  • Ni, X., et al., Int. J. Biochem. Cell Biol. 34(2):109-115 (2002).
  • Zhou, B., et al., Nat. Genet. 28(4):345-349 (2001).
  • Westaway, S.K., et al., Int. J. Biochem. Cell Biol. 34 (12), 1629 (2002) (): ().
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-360 amino acids from the Central region of human PANK1.
NCBI Gene ID #:
53354
NCBI Official Name:
Pantothenate kinase 1
NCBI Official Symbol:
PANK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
Q8TE04
Protein GI Number:
27805665
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8TE04
User NOte:
Optimal dilutions for each application to be determined by the researcher.