ProSci

PSG7 Antibody

Product Code:
 
PSI-61-722
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of PSG7 Antibody in MCF-7 cell line lysates (35ug/lane)
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PSG7 Antibody IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of PSG7 Antibody in MCF-7 cell line lysates (35ug/lane)
PSG7 Antibody IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-61-722-400ul400ul£626.00
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Further Information

Additional Names:
Putative pregnancy-specific beta-1-glycoprotein 7, PS-beta-G-7, PSBG-7, Pregnancy-specific glycoprotein 7, PSG7
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
PSG7 is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene.
Background References:
  • Grimwood, J., et al. Nature 428(6982):529-535(2004)
  • Beauchemin, N., et al. Exp. Cell Res. 252(2):243-249(1999)
  • Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PSG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-293 amino acids from the C-terminal region of human PSG7.
NCBI Gene ID #:
5676
NCBI Official Name:
Putative pregnancy-specific beta-1-glycoprotein 7
NCBI Official Symbol:
PSG7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q13046
Protein GI Number:
108935881
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q13046
User NOte:
Optimal dilutions for each application to be determined by the researcher.