NSJ Bioreagents

FRZB Antibody

Product Code:
 
NSJ-R32294
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the FRZB antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of human 1) PANC and 2) U87 cell lysate with FRZB antibody. Expected/observed molecular weight ~36 kDa.
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Western blot testing of human 1) PANC and 2) U87 cell lysate with FRZB antibody. Expected/observed molecular weight ~36 kDa.

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NSJ-R32294-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,ELISA: 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating
Application Note:
Optimal dilution of the FRZB antibody should be determined by the researcher.
Description:
FRZB is also known as FRE or OS1. The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. FRZB is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. FRZB is localized in the extracellular plasma membrane. Unlike frizzled, frzb lacks the 7 transmembrane domains normally found in G-protein-coupled receptors. It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 176-325 of human FRZB were used as the immunogen for the FRZB antibody.
Limitation:
This FRZB antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q92765