NSJ Bioreagents

ITCH Antibody / AIF4

Product Code:
 
NSJ-R32307
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the ITCH antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of 1) human HeLa, 2) Raji and 3) U937 lysate with ITCH antibody. Predicted molecular weight: ~99 kDa.
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Western blot testing of 1) human HeLa, 2) Raji and 3) U937 lysate with ITCH antibody. Predicted molecular weight: ~99 kDa.

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CodeSizePrice
NSJ-R32307-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the ITCH antibody should be determined by the researcher.
Description:
ITCH is an ubiquitin-conjugating enzyme. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids AMQQFNQRFIYGNQDLFATSQSKEFDPL of human ITCH were used as the immunogen for the ITCH antibody.
Limitation:
This ITCH antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q96J02