NSJ Bioreagents

Stra8 Antibody

Product Code:
 
NSJ-R30770
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the Stra8 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of Stra8 antibody and Lane 1: A231; 2: Jurkat; 3: HT1080; 4: SCG cell lysate. Predicted size: ~37KD
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Western blot testing of Stra8 antibody and Lane 1: A231; 2: Jurkat; 3: HT1080; 4: SCG cell lysate. Predicted size: ~37KD

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CodeSizePrice
NSJ-R30770-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Stra8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Stimulated by retinoic acid 8 is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons and is mapped to chromosome 7q31. Retinoic acid(RA) signaling is required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying expression in embryonic testis. Since RA signaling regulated expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Stra8 (DEEMIMLQCTETFDDEDL) was used as the immunogen for this Stra8 antibody.
Limitation:
This Stra8 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q7Z7C7