The significance of antibody-based in vivo studies For both research and therapeutic purposes, antibodies can be used to affect cellular processes in vivo and are referred to as functional/in vivo grade antibodies. There is a wide range of applications for
The Role of Monoclonal Antibodies & Biosimilars in Life Science Research
mAbs (biosimilars) as tools to research novel new therapies and uncover effective off-target application.
Correlation Between HLA Typing and Immune Monitoring in Human Disease
The human leukocyte antigen system, aka human major histocompatibility complex, was named after its discovery with alloantibodies against leukocytes.
Insights into the Molecular Mechanisms Regulating Necroptosis
This white paper details findings in molecular mechanisms that govern necroptosis related to RIPK & details #2283 use to analyse expression of RIPK3.
A Deep Dive into the Hidden Power of Programmed Cell Death: Unlocking Therapeutic Potential with Antibodies
ProSci has 25+ years of expertise in developing antibodies. This white paper details use of ProSci antibodies in the study of programmed cell death.
Protein Phosphorylation: Essential Role in the Proper Functioning of Pathways
MBLI offers Assay/Inhibitor screening kits designed to measure the activities of purified kinase for the rapid and sensitive evaluation of inhibitors.
S100 Proteins Regulate Metabolic and Immune Pathways to Influence Disease State
Involved in diverse cellular pathways & diseases, S100 proteins play a vital role in intricate workings of cells. MBL has a variety of S100 ELISA kits.
IL-18 Therapies Targeting Inflammatory Disease
MBL International offers a wide variety of products to help in the research of IL-18.
New B7 Family Immune Checkpoint Proteins
Recently 5 new B7 family ligands, B7-H3, B7-H4, B7-H5, B7-H6 & B7-H7, were identified, all of them possibly of high interest in immunotherapy research.
OX40 – OX40L Pathway
OX40 is an activating receptor expressed on the surface of activated cytotoxic T cells & Tregs. OX40 activates & amplifies T cell responses.