AdipoGen’s Progranulin (human) ELISA Kit is the only kit that can detect all mutations in the progranulin gene.
Poly(ADP-ribosyl)ation (PARylation) – An Important Posttranslational Modification
AdipoGen Life Sciences provide high quality reagents for PAR & PARP research
PANoptosis – Inflammatory Cell Death
PANoptosomes are involved in many diseases including autoinflammatory, metabolic & neurodegenerative diseases, cancer & microbial human infections.
FNDC5/Irisin & FNDC4 – Members of the FNDC Protein Family
AdipoGen Life Sciences offers a broad range of FNDC4, FNDC5 and Irisin research reagents, including Recombinant Proteins, Antibodies and ELISA Kits.
SURAMIN – A Multifunctional Small Molecule with over 100 Years of History
Suramin is a multifunctional molecule with a wide array of potential applications, from parasitic and viral diseases to cancer, snakebite and autism.
Resiniferatoxin (RTX) – Potent TRPV1 Agonist for Pain Relief
The plant Euphorbia resinifera contains the most potent irritant known so far. It was isolated and identified as resiniferatoxin (RTX).
Manumycin A – Exosome Biogenesis Inhibitor
Manumycin A is an inhibitor of exosome biogenesis & secretion. Targeting exosome biogenesis could exert RAS signalling inhibitors’ anticancer effects.
Nano Vaccines Induce T Cell Immunity and Control of Tumour Growth
Using nanoparticle technology in making vaccines for infectious diseases/cancer is advancing & enhances the immunogenicity of some vaccine candidates.
Popular Targets for Bispecific Antibody Drugs
Bispecific Antibody drugs gained popularity since approval of blinatumomab. 6 bsAb drugs are approved by the US FDA/EMA & 180+ are in clinical trials.
Is your drug candidate able to reverse the T Cell Exhaustion-like state in MBL’s in vitro functional screening assay?
The process of T cell exhaustion & how it can be harnessed for immuno-oncology drug discovery and for immune checkpoint screening of drug candidates.