SAMHD1, or Sterile Alpha Motif and Histidine/Aspartate domain-containing protein 1, is a dimeric enzyme with phosphohydrolase and nuclease activity that functions as a blockade for virus replication in dendritic cells, monocytes, and macrophages. Its activity is regulated through phosphorylation of
Searching for the Heart of the Problem: Antibodies to Cardiac Myosin Binding Protein
ProSci works with Dr. Sadayappan to create a set of custom antibodies used to study cardiomyopathy. Cardiac Myosin Binding Protein-C (cMyBP-C) is a protein present in cardiac muscle that has been shown to affect the organizational structure of the muscle
Antibody Suppresses AIDS Virus
News from ProSci: Results from a new trial found that an “extremely potent” antibody can dramatically reduce the level of the HIV virus in a patient’s blood. An H9 T cell, blue, is shown infected with HIV, yellow. Researchers at
Does the Llama Hold the Key to HIV Vaccines?
Llamas make especially tiny antibodies that can neutralize 60 strains of HIV. Known for being sturdy and dependable animals, leave it to llamas to deliver some good news in the slow-going quest for an HIV vaccine. (learn more about ProSci’s
Kidney Disease Reagents Available
If you’re researching kidney development or disease, then take a look at the range of products we have to help you. Caltag Medsystems has access to a large number of products for use in basic and clinical research including primary renal
Chocolate Brainteaser
Can you solve our chocolate quiz? If you can name all 10 chocolate bars, please email your answer to paula@caltagmedsystems.co.uk for a chance to win a bumper chocolate surprise next month! Definitely not before 20.01 hours… Voodoo in a box
Albumin Removal from Sample Preparations
Biotech Support Group bring you two alternate strategies for albumin removal from sample preparations: AlbuSorb – an albumin binding strategy AlbuVoid – an albumin voiding strategy plus Albutrial, a combined trial kit including 1 gm of AlbuSorb™ and 5 Preps of AlbuVoid™ with
Blood Controls for Flow Cytometry
Routine haematological testing requires the use of reference material during machine set up such that validation prior to analysis of patient samples can be performed. Many also require repeat use of reference controls throughout the running period of the machine,
Haemoglobin Depletion From Haemolysed Serum and Plasma
Biotech Support Group bring you two alternate strategies for haemoglobin removal from sample preparations for proteomic & genomic sample seperation and enrichment Hemoglobind – a binding strategy recommended for applications where haemoglobin is in relatively low abundance ie haemolysed serum. HemoVoid – a
Lipid Removal and Clarification
The Cleanascite™ reagent has been used extensively across a number of research applications to selectively removes lipids and their constituents (e.g cell debris, transgenic milk and egg yolk) for pretreatment of samples prior to purification. The reagent is a solid-phase,