Leadgene Biomedical Inc. - GMP proteins and all-around solution provider for proteomics studies distributed in the UK by Caltag Medsystems

LeadGene Biomedical

Leadgene Biomedical Inc., founded in 2013 in Taiwan, develop and manufacture quality research tools such as proteins, antibodies, ELISA kits, immunoassay kits, and biochemicals.

Their products are used in a wide range of fields, including academic research, drug discovery and development, and diagnostic development.

Leadgene can also provide custom services, including custom antibody production, protein production, and assay development.

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Nanobody (VHH) Development Service

Leadgene Biomedical offers a Nanobody (VHH Antibody) Development Service, now available at special pricing when you contact us!

GMP-Grade Proteins

Leadgene's GMP-grade proteins are produced in a way that adheres to good manufacturing practices, ensuring they are produced consistently and accurately, and that they meet the required specifications for purity, quality, and safety.

GMP-grade proteins are used as components of cell culture media, or as reagents in the production or purification of cells.

Using GMP-grade proteins can help to minimise the risk of contamination or adverse effects and can help to ensure that the cells used in therapy are of the highest quality.

See all GMP-Grade Products

IVD Raw Materials

Leadgene offers components for the manufacture of in-vitro diagnostic (IVD) products. These ingredients, known as IVD raw materials, are used in the creation of medical diagnostic tests, devices, and reagents for disease diagnosis.

Some of the materials in the collection include antibodies, enzymes, and buffers used in diagnostic test kits.

See all IVD Products

Protein Engineering

Leadgene is a leading provider of premium protein engineering tools, designed to facilitate and expedite your research and development processes.

By leveraging their advanced tools, you can significantly streamline your protein engineering operations, gaining the purity and accuracy you need in your research.

Proteases     Conjugation Kits     Purification Kits     Agarose Beads     See all Protein Engineering Products

Molecular Biology

Polymerase chain reaction (PCR) and reverse transcription-PCR (RT-PCR) are indispensable tools in molecular biology for amplifying specific DNA sequences. They are used in a variety of applications including gene cloning, gene expression analysis, and diagnostics.

Leadgene offers a comprehensive collection of high-quality PCR and RT-PCR reagents and master mix to ensure your results are accurate and sensitive.

DNA Amplification     In Vitro Transcription     CRISPR/CAS9     See all Molecular Biology Products

Antibodies

Primary Antibodies

Leadgene offers an extensive catalogue of monoclonal and polyclonal antibodies, and isotype controls. Their antibodies are validated for use in a range of applications, including enzyme-linked immunosorbent assay (ELISA), Western blotting, immunohistochemistry (IHC), and others.

Monoclonal Antibodies     Recombinant Antibodies     Biosimilars     Isotype Controls     See all Primary Antibodies

Secondary Antibodies

As well as their catalogue of primary antibodies, Leadgene provide a range of secondary antibodies. These are commonly used in laboratory techniques such as Western blotting, ELISA, immunohistochemistry, and lateral-flow assay to detect the presence or expression of antigens of interest in a sample.

See all Primary Antibodies     See all Antibodies

Recombinant Proteins

Leadgene offers a line of RUO-grade proteins, carefully designed to meet your diverse research needs. This range includes cytokines, growth factors, chemokines, and more, offering you a wide array of choices for your experimental design.

Leadgene ensures high purity and stability of their proteins to guarantee reliable results. Their expression systems cater to diverse requirements, providing proteins derived from both E. coli and mammalian cells.

Cytokines     Chemokines     Growth Factors     See all Recombinant Proteins

Cell Biology Reagents

Leadgene's cell biology reagents are meticulously designed to enhance your cell-based research. Whether you're working with primary cells or cell lines, conducting in-vitro studies, or exploring cellular pathways, Leadgene's Cell Biology Reagents provide the reliability and performance to ensure the success of your experimental procedures.

See all Cell Biology Reagents

ELISA Kits

Leadgene offers a growing catalogue of ELISA kits for your research or diagnostic needs. Each kit comes packaged with all the necessary reagents and materials, including a microplate, specific antibodies, and detection reagents. Results can be easily read visually or with instrumentation for guaranteed quality results.

See all ELISA Kits

LEADSPHERE® Lyophilisation Technology

Some of Leadgene's products are produced using their innovative LEADSPHERE® lyophilisation technology.

LEADSPHERE® lyophilisation technology serves as a platform to ease the development of reagents in lyophilised and stable sphere format while maintaining the components' bioactive condition at room temperature for at least 12 months.

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The Benefits of LEADSPHERE® Lyophilisation Technology:

  • Facilitation of long-term logistics at room temperature
  • Ease in aliquoting and handling during the manufacturing process
  • Simplifying point-of-care protocol for end-users

Molecules that can be produced using LEADSPHERE® technology: Antibodies, Proteins, Enzymes, Chemicals, PCR Mixture.

Leadgene Biomedical's products are supported by a quality management system that is certified for ISO 13485:2016 and Good Manufacturing Practices (GMP).

See all LEADSPHERE® Lyophilisation Technology Products

Viral Infections

Leadgene offer a range of products for viral infections including Influenza, Coronavirus, Respiratory Syncytial Virus (RSV), Monkeypox virus (MPXV), Dengue Fever virus (DENV), Zika virus (ZIKV) and others.

Blog posts

Quantitatively Detect Residual Protease in Samples

LeadGene ELISA kits to quantitatively detect residual protease in samples.

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Leadgene Utilizes LEADSPHERE™ Lyophilization Technology to Make Reagents Stable for Long-Term Logistics - Press release

Leadgene Biomedical has announced the launch of LEADSPHERE™ Lyophilization Technology to aid in the dispense, storage, and transport of their reagents

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LEADGENE® Indoxyl Sulfate ELISA Kit: Rapid Detection and Surveillance of Chronic Kidney Disease

LEADGENE® Indoxyl Sulfate ELISA Kit is the first CE-registered antibody-based assay tool for chronic kidney disease (CKD) on the global market.

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Documents

  Category Title  
Leadgene Indoxyl Sulfate (IS) ELISA Kit Instructions for UseDatasheets DocumentsLeadgene Indoxyl Sulfate (IS) ELISA Kit Instructions for Use  View
Leadgene Indoxyl Sulfate (IS) ELISA Kit is a competitive enzyme-linked immunosorbent assay (competitive ELISA) for quantitative detecting total indoxyl sulfate (IS) levels in human serum samples. It is used as an aid in the diagnosis of renal function. However, it is intended for in vitro diagnostic use only, NOT suitable for use in therapeutic procedures.  
Indoxyl Sulfate ELISA Diagnostic KitELISA DocumentsIndoxyl Sulfate ELISA Diagnostic Kit  View
A novel method for CKD Diagnostic  
Leadgene Indoxyl Sulfate (IS) ELISA KitELISA DocumentsLeadgene Indoxyl Sulfate (IS) ELISA Kit  View
An overview of the formation and effect of Indoxyl Sulfate  
Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axisCitations DocumentsIndoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis  View
Sarcopenia or frailty is common among patients with chronic kidney disease (CKD). The protein-bound uremic toxin indoxyl sulfate (IS) is associated with frailty. IS induces apoptosis and disruption of mitochondrial activity in skeletal muscle. However, the association of IS with anabolic myokines such as irisin in patients with CKD or end-stage renal disease (ESRD) is unclear. This study aims to elucidate whether IS induces frailty by dysregulating irisin in patients with CKD.  
Assessment of ELISA-based method for the routine examination of serum indoxyl sulfate in patients with chronic kidney diseaseCitations DocumentsAssessment of ELISA-based method for the routine examination of serum indoxyl sulfate in patients with chronic kidney disease  View
The IS ELISA kit from Leadgene exhibits a comparable capability, high agreement and correlation to UPLC-MS/MS in the quantification of total serum IS levels and would be suitable for dynamic monitoring of serum IS levels in patients with CKD.  
GMP-grade ProteinsProteins DocumentsGMP-grade Proteins  View
The Good Manufacturing Practice (GMP) ensures quality standards for manufacturing products. As the potential of cellular therapies continues to increase, the demand for GMP cytokines and growth factors also rises. Leadgene provides a safe and traceable supply of GMP proteins for ex vivo cell culture in the manufacturing of cell therapy treatment.  
EnzymesProteins DocumentsEnzymes  View
Discover the power of innovation with Leadgenes portfolio of enzymes for molecular biology and protein engineering. Our expert and skilled team develops and manufactures all products in-house, guaranteeing premium quality for your research needs.  
LeadGenes Standard AntibodyAntibodies DocumentsLeadGenes Standard Antibody  View
Secure precision in your diagnostic assays. Use Standard Antibody as the positive control for the development of Antibody Detection Assays.  
PNGase FlyerMolecular Biology DocumentsPNGase Flyer  View
Leadgene offers premium Deglycosylation Enzymes for Vaccines and Antibody-Drug Conjugates.  
Proteins VideosLEADGENE® GMP-Grade Proteins  View
Leadgenes manufacturing capabilities include the production of a broad array of high-quality recombinant proteins, inclusive of a comprehensive human cytokine panel designed for immunology and cancer research. In addition, they also provide GMP-grade proteins from their ISO 13485 certified facility. These GMP-grade proteins are ideally suited for studies involving ex vivo cellular expansion, polarisation, or differentiation.  
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