UK and Ireland Distributor of Signosis - Biomarker Analysis, Plate Assay Development, Arrays, Cytokines, ELISA and EMSA

Cytokines and Hormones

Transcription Factor Assays

Signosis

Signosis is a molecular tool company focusing on the development of innovative and unique products for biomarker discovery and analysis in life science research, clinic application and drug discovery.

The Signosis product portfolio currently includes miRNA arrays, miRNA northern blot assay kits, miRNA plate assays, phospho-antibodies, obesity ELISA kits, cancer ELISA kits and cardiac marker ELISA kits.

Cytokine Analysis - Signosis provides a number of tools to profile single cytokines, or to monitor multiple cytokines simultaneously.
Transcription Factor Assays - a number of assays to facilitate the analysis of transcription factors are available. The TF Activation Profiling Plate Arrays and Promoter-Binding TF Profiling Array are for the analysis of multiple TFs, and TF Filter Plate Assays, EMSA Kits, Luciferase Reporter Vectors, Luciferase Stable Cell Lines, and TF Western Blot Detection Assay Kits can monitor individual TFs.
Cell Lines and Frozen Cells - A series of gene expression- or luciferase reporter-ready stable cell lines are available plus hundreds of transfected frozen cells. The cells can be re-cultured and treated with any stimuli for further study. The cells can be used for a variety of assays, such as luciferase reporter assay, ELISA, RT-PCR, western blotting, and Co-IP.
miRNA Research - A variety of innovative tools for the research of miRNAs including miRBNA arrays for profiling multiple miRNAs simultaneously or to monitor one specific miRNAs are available.
Gene Expression Analysis - a number of assay products for gene expression studies are available including the cDNA Plate Arrays for monitoring the expression of genes that are up or down regulated by TFs, and the single cell PCR kits for analyzing gene expression, which allows direct analysis of cell lysates without RNA isolation prior assay.
Protein Interaction Analysis - Signosis provides a number of innovative tools for the research of protein-protein interactions, such as the signaling protein assays, and the Co-Immunoprecipitation kits.
Biomarker Analysis - Signosis provides a variety of biomarkers for autoimmune, cardiac, and tumour diseases. With the tools, certain diseases can be detected more efficiently.
siRNA Plate Assay Kit
mRNA capture Plate Assays

Documents

Category	Title
Transcription Factors Documents	Solutions for Transcription Factor Research	View
Signosis provides several different tools to facilitate the analysis of transcription factors. The multifunctional products are designed to meet different needs, and contribute to exciting research results.
Transcription Factors Documents	Stem Cell TF Activation Profiling Plate Array	View
Multiple transcription factors (TFs) have been reported to associate with stem cell self-renewal and pluripotency such as EGR1, OCT4, FOXD3, FOXO, Nanog, SOX2, SOX18, ETS, GLI, KLF4, MEF2, Myc, RNUX1, Pax6, TCF/LEF and GATA. Analyzing the activities of these TFs can provide valuable insight into the study of stem cells. Signosis has developed Stem Cell Transcription Factor Activation Plate Array to analyze the activities of 16 stem cell related TFs simultaneously for mammalian samples. The assay can be used with the whole cell lysate from 1000-10000 cells.
RT-PCR Documents	Single Cell RT-PCR Assay Kit	View
Signosis has developed a sensitive single cell RT-PCR directly cell lysates without RNA preparation. Therefore, a small number of cells is enough for RT-PCR analysis. Signosis now offers the optimized buffers for subsequent RT-PCR, which followed cell lysis with CL™ cell lysis buffer. All of reagents for cDNA synthesis and PCR amplification in addition to CL™ cell lysis buffer are included in the kit.