Further Information
Pgp-1, H-CAM, ECMR-III, HUTCH-1
CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, CMCD, cytotoxicity, depletion, adhesion, activation, purification, and blocking assays.
CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
0.1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Purified human T cells
960
CD44 molecule (Indian blood group)
CD44
Homo sapiens
Liquid
P16070
Signal Transduction,Signal Transduction
CD44
P16070
Optimal dilutions for each application to be determined by the researcher.