ProSci

CD44 Antibody [F10-44-2]

Product Code:
 
PSI-99-380
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[F10-44-2]
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Frozen Section (IHC-F)
Shipping:
 
blue ice
Storage:
 
Store vial at -20˚C
1 / 1
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PSI-99-380-0.5mg0.5mg£782.00
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Further Information

Additional Names:
Pgp-1, H-CAM, ECMR-III, HUTCH-1
Application Note:
CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, CMCD, cytotoxicity, depletion, adhesion, activation, purification, and blocking assays.
Background:
CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
Buffer:
Supplied in PBS
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Purified human T cells
NCBI Gene ID #:
960
NCBI Official Name:
CD44 molecule (Indian blood group)
NCBI Official Symbol:
CD44
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P16070
Research Area:
Signal Transduction,Signal Transduction
SPECIFICITY:
CD44
Swissprot #:
P16070
User NOte:
Optimal dilutions for each application to be determined by the researcher.