Antibody Clonality:
Monoclonal
Applications:- Immunohistochemistry- Frozen Section (IHC-F)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store vial at 2-8˚C
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Lyt-1, Ly-1, Lymphocyte antigen 1, Ly-12, Ly-A, T1, Tp67
CD5 Antibody [B19.1] for use in flow cytometry, western blotting, and immunoprecipitation assays.
CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
0.5 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
12507
CD5 antigen
Cd5
Mus musculus
Liquid
P13379
Cancer,Immunology,Signal Transduction
CD5
P13379
Optimal dilutions for each application to be determined by the researcher.