CD62E/CD62P Antibody [1.2B6]
Antibody Clonality:
Monoclonal
Application:
Flow Cytometry
Storage:
Store vial at 2-8˚C
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
E-selectin, P-selectin, ELAM-1, LECAM-2, PADGEM, GMP-140, LECAM-3
CD62E/CD62P Antibody [1.2B6] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ELISA, adhesion, and blocking assays.
CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
0.1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
TNF stimulated human endothelial cells
6401
E-selectin
SELE
Homo sapiens
Liquid
P16581
Immunology,Signal Transduction
CD62E/CD62P
P16581
Optimal dilutions for each application to be determined by the researcher.