ProSci

FGF-23 Antibody [FGF23/638]

Product Code:
 
PSI-33-227
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
FGF23/638
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Functional Study
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
 

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PSI-33-227-100ug100ug£765.00
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Further Information

Additional Names:
Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor
Application Note:
ELISA: order BSA-free format for coating

Functional testing: order BSA/azide-free format

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FGF-23 antibody to be titered up or down for optimal performance.
Background:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi), FGF5, FGF6, FGF7 (KGF), FGF8 (AIGF), FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant human FGF-23 protein was used as the immunogen for this antibody.
NCBI Gene ID #:
8074
NCBI Official Name:
fibroblast growth factor 23
NCBI Official Symbol:
FGF23
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G purified FGF-23 antibody
Research Area:
Obesity
Swissprot #:
Q9GZV9
User NOte:
Optimal dilutions for each application to be determined by the researcher