ProSci

GBL Antibody

Product Code:
 
PSI-33-065
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
1 / 1
Western blot testing of human samples with GBL antibody at 1ug/ml.
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Western blot testing of human samples with GBL antibody at 1ug/ml.

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CodeSizePrice
PSI-33-065-100ug100ug£662.00
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This product comes from: United States.
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Further Information

Additional Names:
GBL Antibody: GBL, LST8, POP3, WAT1, GbetaL, GBL, Target of rapamycin complex subunit LST8, G protein beta subunit-like, TORC subunit LST8
Application Note:
Western blot: 1-3 ug/ml

Provided assay concentrations are suggestions only, GBL antibody titration may be required for optimal results.
Background:
GBL (G protein beta subunit-like), also called MLST8 (MTOR associated protein, LST8 homolog), is a subunit of the mTOR signaling complexes mTORC1 and mTORC2, which help regulate cell growth and survival in response to growth factor (mTORC1 & 2) and nutrient (mTORC1) signaling. It is required for the phosphorylation of S6 kinase and the signal adaptor protein Insulin receptor substrate 1 and S473 phosphorylation of AKT. GBL is also a regulator of TNFa-induced NF-kB activity, with overexpression inhibiting and down-regulation enhancing NF-kB signaling (Kim et al, 2008).
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the internal region of human GBL was used as the immunogen for this antibody.
NCBI Gene ID #:
64223
NCBI Official Name:
G protein beta subunit-like
NCBI Official Symbol:
MLST8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Signal Transduction
Swissprot #:
Q9BVC4
User NOte:
Optimal dilutions for each application to be determined by the researcher