ProSci

IGF1 Antibody [M23]

Product Code:
 
PSI-33-144
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
M23
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rabbit
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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SDS-PAGE Analysis of Purified, BSA-Free IGF1 Antibody (clone M23). Confirmation of Integrity and Purity of the Antibody.
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SDS-PAGE Analysis of Purified, BSA-Free IGF1 Antibody (clone M23). Confirmation of Integrity and Purity of the Antibody.

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PSI-33-144-100ug100ug£765.00
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Further Information

Additional Names:
IGF1, OTTHUMP00000195084, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor 1, IGFI, IGF1A, IBP1
Application Note:
Flow Cytometry: 0.5-1 ug/million cells

IF: 1-2 ug/ml

Functional Activity: In vitro inhibition of IGF1 Activity; order BSA/azide free format

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Background:
This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Purified human IGF1 protein was used as the immunogen for this antibody.
NCBI Gene ID #:
3479
NCBI Official Name:
insulin-like growth factor 1 (somatomedin C)
NCBI Official Symbol:
IGF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Immunology
Swissprot #:
P05019
User NOte:
Optimal dilutions for each application to be determined by the researcher