ProSci

CD1b Antibody [RIV12]

Product Code:
 
PSI-33-078
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
RIV12
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Functional Study
  • Immunofluorescence (IF)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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FACS staining of human PBMCs using CD1b antibody (RIV12).
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FACS staining of human PBMCs using CD1b antibody (RIV12).

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PSI-33-078-100ug100ug£765.00
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Further Information

Additional Names:
T-cell surface glycoprotein CD1b, CD1b, CD1B
Application Note:
Functional testing: order BSA/azide free format

IF: 0.5-1 ug/ml

Flow Cytometry: 0.5-1 ug/million cells in 0.1ml

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD1b antibody to be titered up or down for optimal performance.
Background:
This antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.
NCBI Gene ID #:
910
NCBI Official Name:
CD1b molecule
NCBI Official Symbol:
CD1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Immunology
Swissprot #:
P29016
User NOte:
Optimal dilutions for each application to be determined by the researcher