Nordic MuBio

Rabbit anti Human SSRP1 NT

Product Code:
 
EXA-X1586P
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Shipping:
 
Ship at ambient temperature freeze upon arrival
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-X1586P100 ug£316.00
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Further Information

Applications Description:
Antibody can be used for Western blotting (5-10 ?g/ml) and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.
Background:
SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Recombinant protein consisting of amino acids 1-242 of the human SSRP1 protein.
Positive Control:
Not Available
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Ammonium Sulfate Precipitation
UniProt:
Q08945

References

1. Keller, D.M., et al. 'A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSPT16 and SSRP1.' Mol. Cell Biol. 2001, 7, 283-292