Nordic MuBio

Mouse anti Human p130

Product Code:
 
EXA-N105M
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
KAB40
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Room Temperature
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-N105M100 ug£316.00
Quantity:
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Further Information

Applications Description:
Western Blots at 1:1000
Background:
The immunogen used was a recombinant protein to the N terminus of p130. p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Cell Cycle
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Recombinant protein to the N terminus of p130
Positive Control:
This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. And is suitable for use in western blot with his- tagged or GST tagged proteins.
Product:
Monoclonal antibody provided as solution in phosphate buffered saline with 0.08% sodium azide
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Protein A/G Chromatography
Source:
The immunogen used was a recombinant protein to the N terminus of p130.
Synonyms:
p130; Retinoblastoma-like protein 2; RBR-2; PRB2
UniProt:
Q08999 (Human) Q64700 (Mouse) O55081 (Rat)