NSJ Bioreagents

Raf1 Antibody / c-Raf

Product Code:
 
NSJ-RQ5033
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
IAG-18
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the c-Raf antibody at -20°C.
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Western blot testing of human HeLa cell lysate with c-Raf antibody. Predicted molecular weight ~73 kDa.
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Western blot testing of human HeLa cell lysate with c-Raf antibody. Predicted molecular weight ~73 kDa.

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NSJ-RQ5033-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:500-1:5000
Application Note:
Optimal dilution of the c-Raf antibody should be determined by the researcher.
Description:
Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). [UniProt]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Raf1 was used as the immunogen for the c-Raf antibody.
Limitation:
This c-Raf antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P04049